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Anxiety and depression are serious mental health conditions that affect millions of people every day. They can make it hard to sleep, focus, work, or enjoy life. While therapy and medications are often helpful, some people don’t get the relief they need from traditional treatments. One lesser-known option that’s gaining renewed attention is a procedure called a stellate ganglion block (SGB), which has been used for nearly a century and is now being explored for its potential mental health benefits.
What is a Stellate Ganglion Block for Mental Health?
The stellate ganglion is a bundle of nerves in the neck. These nerves are part of the sympathetic nervous system, which controls the body’s “fight or flight” response. When you’re constantly anxious or stressed, this part of the nervous system may become overactive.
A stellate ganglion block is a small injection of local anesthetic into this area. The goal is to calm the nerves and “reset” the system, helping the body return to a more balanced state.
How Stellate Ganglion Block Reduces Anxiety and Depression Symptoms
When someone has chronic anxiety or post-traumatic stress, their body may stay in a constant state of alert. This can make it difficult to relax or feel safe, even in normal situations. A stellate ganglion block injection for depression and anxiety can interrupt this cycle by temporarily blocking the overactive nerve signals.
After the block, many people report feeling calmer, more clear-headed, and emotionally stable. For some, the relief happens within minutes or hours. For others, it may take a few days.
Who Can Benefit from Stellate Ganglion Block Treatment?
SGB was first used to help military veterans with post-traumatic stress disorder (PTSD), but now it’s being explored for people with:
- Severe anxiety
- Depression linked to trauma
- Panic disorders
- Chronic stress
It’s especially helpful for people who haven’t found success with therapy, medication, or other treatments. It may also be a good option for those who want faster relief.
What to Expect During the Stellate Ganglion Block Injection for Anxiety & Depression
The SGB procedure is usually done in a medical office or outpatient clinic. You’ll lie down while a doctor uses ultrasound or X-ray to guide a small needle into your neck near the stellate ganglion. A local anesthetic is then injected to block the nerve signals.
The whole procedure takes less than 30 minutes, and most people go home the same day. Some feel tired or slightly dizzy afterward, but serious side effects are rare.
How Long Stellate Ganglion Block Relief for Anxiety & Depression Lasts
Relief from a stellate ganglion block for depression and anxiety can last for weeks or even months. In some cases, people may need more than one block to get the best results. If symptoms return, the procedure can usually be repeated safely.
Doctors are still studying exactly how long the benefits last and how often it should be done. But early research and patient stories show that it can be a powerful tool for mental health recovery.
Common Side Effects and Safety of a Stellate Ganglion Block for Anxiety & Depression
Like any medical procedure, there are risks, but a stellate ganglion block for depression and anxiety is generally considered safe. Side effects are usually mild and may include:
- Temporary hoarseness
- Eye drooping
- Warm feeling in the arm or face
These effects go away after a few hours. It’s important to have the procedure done by a trained professional to reduce the chance of complications.
What Recovery Looks Like After a Stellate Ganglion Block
Most people recover quickly after receiving a stellate ganglion block for depression and anxiety. Right after the injection, you may feel some temporary side effects, such as a warm sensation in your face or arm, slight drooping of your eyelid, or mild hoarseness. These effects are normal and usually fade within a few hours.
You’ll rest briefly at the clinic, so your medical team can make sure you’re feeling okay before you go home. It’s best to have someone drive you in case you feel lightheaded or tired afterward.
Once home, most people are able to resume normal activities the same day or the following day. Some individuals report feeling a sense of calm or mental clarity within hours, while for others, the full emotional relief may develop over several days.
There is no major downtime, and most people return to work or school shortly after the procedure. However, it’s a good idea to avoid strenuous activities for the rest of the day and give your body time to adjust. If any side effects last longer than expected, it’s important to contact your provider.
Combining a Stellate Ganglion Block with Other Mental Health Treatments for Anxiety & Depression
A stellate ganglion block can offer powerful relief from anxiety and depression, but it’s most effective when paired with other mental health treatments. Many people continue working with a therapist, attending support groups, or receiving medication management while receiving SGB. Some also benefit from mental health housing services—a supportive environment that offers a balance of independence and structure, helping individuals focus on healing while building life skills and healthy routines.
The procedure may help reduce the overwhelming emotional symptoms that sometimes make it hard to fully engage in therapy. With a calmer nervous system, individuals may feel more present, open, and focused, making it easier to explore their thoughts and emotions during counseling.
Using SGB as part of a broader treatment plan gives people more tools to manage their mental health. When combined with consistent care and healthy support systems, it can help create lasting improvements in emotional well-being.
How a Stellate Ganglion Block Compares to Other Therapies
Compared to other treatments like antidepressants, talk therapy, or transcranial magnetic stimulation (TMS), SGB works quickly. Some people who don’t respond well to traditional care find that SGB helps when other methods have not. It’s not meant to replace other treatments—but for many, it adds another layer of support.
Who Should Avoid a Stellate Ganglion Block?
While SGB is safe for many people, it’s not right for everyone. People with bleeding disorders, infections near the injection site, or certain heart or neck conditions may not be eligible. Your doctor will review your health history before moving forward.
A Supportive Path Toward Mental Wellness
Mental health is deeply personal, and what works for one person may not work for another. A stellate ganglion block is not a cure, but it can be a powerful part of a full recovery plan. For those living with anxiety, depression, or trauma-related symptoms, this procedure might offer the calm and clarity they’ve been searching for.
At Experience Structured Living in the San Diego area, we offer a customized living experience for those with mental health conditions. Our mission is to support individuals on their journey to long-term healing. If you or someone you love is interested in exploring stellate ganglion block treatment, we can help connect you with trusted providers. We refer clients to our partner, Thrive Medical Specialists, a highly respected team experienced in performing SGB for anxiety, depression, and trauma-related disorders.
By working together, we ensure our clients receive compassionate care both inside and outside of our program. Whether you’re receiving structured mental health support with us or beginning to explore new treatment options, we’re here to guide you every step of the way.
You deserve support that works—and we’re here to help you find it.
FAQs About How a Stellate Ganglion Block (SGB) Can Help with Anxiety & Depression
How soon should I expect to feel better after the stellate ganglion block procedure for anxiety and depression?
Some people notice a difference within minutes or hours, while others may take a few days. The response can vary based on the individual and the severity of symptoms.
How many stellate ganglion block treatments will I need for anxiety and depression?
Some people feel lasting relief after one treatment, while others may benefit from two or more sessions spaced out over time. Your provider will make a plan based on your response and goals.
Does the stellate ganglion block work for all types of anxiety?
SGB is most commonly used for anxiety that is connected to trauma or chronic stress, such as PTSD. It may not be as effective for all types of generalized anxiety, but it can still help certain individuals.
Is a stellate ganglion block for anxiety and depression permanent?
The effects are not permanent, but they can last for several weeks or months. Some people choose to have the procedure repeated if their symptoms return.
Can the stellate ganglion block procedure for anxiety and depression affect my memory or personality?
No. SGB does not change who you are. It helps reduce the physical and emotional symptoms related to anxiety and depression, allowing you to feel more balanced and in control.
How do I know if I'm a good candidate for a stellate ganglion block for anxiety and depression?
People with anxiety or depression that has not improved with therapy or medication may be good candidates. A medical evaluation is needed to decide if the procedure is safe and appropriate for you.
Dr. Melden earned his Doctorate in Osteopathic Medicine at Philadelphia College Osteopathic Medicine and went to USC Presbyterian Hospital for his residency in Family Medicine. He then completed his Psychiatric residency at the University of California, Irvine and went to UCSD Geropsychiatry pursuing a fellowship. Dr. Melden has over 14 years of experience as a clinician specializing in treating child and adolescent, adult and geriatric clients. He has devoted his life to psychiatry in a variety of different treatment settings including in- patient and out-patient environments. He specializes in the psychiatric evaluation, complementary therapy approaches, and medical management of individuals suffering from mental illness. Currently, he maintains a private practice with Crownview Medical Group in Coronado and Carlsbad, California where he is CEO/President.
